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HPE P54549-B21 10TB 7.2K-RPM SAS 12Gb/s LFF 3.5 HDD
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HPE P54549-B21 10TB 7.2K-RPM SAS 12Gb/s LFF 3.5 HDD
P54549-B21
- 10TB Massive Enterprise Storage
- 7,200 RPM Business Critical Performance
- Ultra-Fast SAS 12Gb/s Interface
- 3.5" LFF Form Factor
- Advanced Helium-Sealed Design
- Instant Secure Erase (ISE) Support
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HPE P54549-B21 10TB 7.2K-RPM SAS 12Gb/s LFF Hard Drive
The HPE P54549-B21 is a genuine 10TB SAS Business Critical Helium hard drive built for enterprise storage environments where capacity, reliability, and data security are absolutely critical. Spinning at 7,200 RPM with a data transfer rate of 1200 Mbps (external) and an 8.0ms average seek time, it is engineered to deliver high sustained throughput and dependable performance for bulk storage workloads. The 12Gb/s SAS interface provides a stable, high-throughput connection, which is exactly what ProLiant Gen8 through Gen10 servers are built around.
What sets this drive apart is its helium-sealed design, which reduces internal friction and power consumption while allowing for higher storage densities and improved reliability compared to traditional air-filled drives. The drive features a 512e Advanced Format sector format for improved data integrity and broad compatibility with modern operating systems. It also features Digitally Signed (DS) firmware, which helps prevent unauthorized access to your data and protects against malicious attacks. Instant Secure Erase (ISE) technology simplifies the cost and complexity of re-purposing or disposing of drives while protecting data — critical for compliance-driven environments. As a Business Critical (BC) class drive, it offers enterprise-class reliability for 24/7 data center operations. It comes with an HPE SmartDrive Carrier (SC) pre-attached, featuring system status LEDs and a "Do-Not-Remove" button to prevent accidental drive removal, making it ready for hot-plug installation in compatible ProLiant systems.
All HPE hard drives pass a rigorous qualification process, which certifies that every drive is proven to perform in your HPE ProLiant Server environments. Because this is a genuine HPE component rather than a generic or rebadged drive, it carries original HPE firmware and a genuine HPE security sticker. That matters when you're replacing a drive in a live production server — mismatched or unverified parts can cause RAID rebuild failures, performance degradation, or even system crashes.
Specifications of HPE P54549-B21 SAS Hard Drive
General Information
Technical Information
Interfaces/Ports
Physical Characteristics
Miscellaneous
Compatibility Guide for HPE P54549-B21 SAS Hard Drive
This HPE P54549-B21 10TB SAS hard drive is built for HPE ProLiant server environments requiring high-capacity 3.5" LFF storage with enterprise-grade reliability and data security. It features a 12Gb/s SAS interface, 7,200 RPM spindle speed, helium-sealed design, Instant Secure Erase (ISE), and SmartDrive Carrier (SC) compatibility for Gen8, Gen9, and Gen10 server families with 3.5" LFF drive bays.
HPE ProLiant Gen10 Servers:
- ProLiant DL160 Gen10
- ProLiant DL360 Gen10 (3.5")
- ProLiant DL380 Gen10 (3.5")
- ProLiant DL385 Gen10 (3.5")
- ProLiant DL385 Gen10 Plus (3.5")
- ProLiant DL388 Gen10
- ProLiant DL560 Gen10
- ProLiant ML350 Gen10
HPE ProLiant Gen9 Servers:
- ProLiant BL460c Gen9
- ProLiant DL20 Gen9
- ProLiant DL60 Gen9
- ProLiant DL80 Gen9
- ProLiant DL120 Gen9
- ProLiant DL160 Gen9
- ProLiant DL180 Gen9
- ProLiant DL388 Gen9
- ProLiant DL560 Gen9
- ProLiant ML110 Gen9
- ProLiant ML150 Gen9
- ProLiant ML350 Gen9
HPE ProLiant Gen8 Servers:
- ProLiant BL420c Gen8
- ProLiant BL460c Gen8
- ProLiant BL465c Gen8
- ProLiant DL120 Gen8
- ProLiant DL160 Gen8
- ProLiant DL320e Gen8
- ProLiant DL360e Gen8
- ProLiant DL380e Gen8
- ProLiant DL380p Gen8
- ProLiant DL388e Gen8
- ProLiant DL560 Gen8
- ProLiant ML310e Gen8
- ProLiant ML350e Gen8
HPE Storage Arrays:
- HPE D3600 (3.5" LFF)
- HPE D3700 (3.5" LFF)
- HPE StoreEasy 1660
- HPE StoreEasy 1660 Performance
HPE Nimble Storage dHCI:
- Nimble Storage dHCI Large Solution with HPE ProLiant DL380 Gen10
- Nimble Storage dHCI Medium Solution with HPE ProLiant DL360 Gen10
- Nimble Storage dHCI Small Solution with HPE ProLiant DL360 Gen10
Compatibility Notes:
- For use with Gen8, Gen9, and Gen10 servers with 3.5" LFF SmartDrive Carrier (SC) drive bays.
- Not for use with 2.5" SFF drive bays — use the correct SFF drive model instead.
- Not for use with HPE MSA storage arrays — MSA drives use different firmware and carriers.
- This drive includes a SmartDrive Carrier (SC) pre-attached for hot-plug installation.
- Firmware revision must match existing drives in the RAID set to avoid rebuild failures. Contact us for firmware match verification.
- If unsure about compatibility, contact us for a free verification check.
Why Buy the HPE P54549-B21 10TB SAS Hard Drive?
When you're expanding storage in an active production server, the difference between a genuine HPE drive and an unverified clone shows up the first time you need to rebuild a RAID set. The HPE P54549-B21 is HPE-manufactured with Digitally Signed Firmware, a helium-sealed design, 512e Advanced Format, Instant Secure Erase (ISE), a genuine HPE security sticker, and an HPE SmartDrive Carrier included. This means it carries the firmware and mechanical tolerances your server's controller already expects — no compatibility guesswork, no risk of a failed rebuild because of a mismatched drive. Here's what makes this HPE P54549-B21 10TB SAS hard drive worth choosing over a cheaper, unverified alternative:
- 100% Genuine HPE Business Critical Part
- 10TB Massive Capacity Storage
- 7,200 RPM Business Critical Performance
- Ultra-Fast 12Gb/s SAS Throughput
- Advanced Helium-Sealed Design
- 512e Advanced Format Support
- Digitally Signed (DS) Firmware
- Instant Secure Erase (ISE) Technology
- HPE SmartDrive Carrier Included
- Hot-Swap Capable Design
Where to Use the HPE P54549-B21 10TB SAS Hard Drive
This HPE P54549-B21 10TB SAS hard drive fits teams maintaining ProLiant server infrastructure who need massive, secure, and reliable storage for demanding workloads. Common deployment scenarios include:
- ProLiant Gen8-Gen10 LFF Server Deployments
- Data Lakes and Cold Storage
- Backup and Archival Systems with Secure Erase Requirements
- Compliance-Driven Data Storage (HIPAA, GDPR, PCI-DSS)
- Data Warehousing and Analytics
- Virtualized Server Environments (VMware)
- Enterprise Backup Server Systems
- Bulk Storage and RAID Arrays
- Surveillance and Video Archiving
Why Choose Us for HPE P54549-B21 10TB SAS Hard Drive
We supply genuine HPE storage to data centers, MSPs, and enterprise IT teams that cannot afford rebuild failures. Our focus is on exact part matching, fast dispatch, and technical verification before shipping.
- 100% Genuine HPE Parts
- Free Compatibility Verification Service
- 90-Day Warranty on Refurbished
- 1-Year Limited New Warranty
- Same Day Shipping Available
- 24/7 Expert Technical Support
- HPE SmartDrive Carrier Included
- Bulk Spare Inventory Available
- 5-Star Rated Service for HPE
FAQs
What does Instant Secure Erase (ISE) mean for my data security?
Instant Secure Erase is a hardware-based feature that cryptographically erases the drive's internal encryption key, rendering all data on the drive unrecoverable in seconds. This is critical for compliance-driven environments (HIPAA, GDPR, PCI-DSS) when drives are retired, re-purposed, or returned under warranty. The P54549-B21 includes ISE, making secure drive disposal fast and auditable without physical destruction.
Is the HPE P54549-B21 compatible with my ProLiant Gen10 or Gen9 server?
Yes, the P54549-B21 is fully validated for ProLiant Gen8, Gen9, and Gen10 servers with 3.5" LFF drive bays, including DL360 Gen10, DL380 Gen10, DL385 Gen10, ML350 Gen9, DL380 Gen9, and DL160 Gen9 models. This drive uses a SmartDrive Carrier (SC), so it will only fit servers with SC-compatible 3.5" LFF drive bays. Our free compatibility verification confirms your exact server model and backplane revision before shipping.
Can I order multiple HPE P54549-B21 drives for a spare pool or array expansion?
Yes. We stock bulk quantities of the P54549-B21, including 2-pack and 10-pack configurations for larger deployments. Volume pricing is available, and we can pre-verify firmware across the entire batch so every drive is rebuild-ready. Contact us with your required quantity and server models for a quote.